Micro Bridle device for determining and monitoring perimeter of alive or inanimate structures.
GTQ and Seville University has developed a low cost (micro)opto-mechanical bridle device for determining and/or monitoring with high precision, during long periods, changes in the size or section of structures with geometry, composition, hardness, dimension and diverse nature. Perimeter changes are used as a control and quality parameter of structures in areas such as medicine (blood vessels), agriculture (plants growing, trees) or industry.
An offer for Patent Licensing and/or R+D+i collaboration
User friendly, robust and low cost bridle device
The microbridle device is manufactured with a flexible and transparent material, such as PDMS or another with similar characteristics. The device consists of a fixation area - where the structure is set to be monitored -, a (micro) cantilever sensor - flexible and mobile - which responds to changes in the structure section and an optical sensor as the signal transduction element. The light intensity collected at the transduction element will change depending on the angle of inclination of the (micro) cantilever, which is proportional to the diameter changes of the structure.
Micro bridle device
scheme and photography.
Monitoring of blood vessels, vegetable structures, conduits ...
Changes in structures section have been evaluated so far, by simple visual inspection and quantitatively by measuring tapes. All these systems are not very accurate and do not allow real-time monitoring of structure changes.
Recently, have been appeared image retrieval systems that allow automatic tracking, but they are expensive and they have large technical limitations (loss of focus, single plane image, contrast between sample and media, influence of environmental factors such as light, humidity, etc.). Pressure Myography is an example of these techniques, used for blood vessels studies, but it suffers the same problems as mentioned above because it requires CCD cameras for changes monitoring.
(M)OEMS developed device provides, in this field, a simple system for monitoring “in real time” contraction-expansion cycles of resistance arteries.
Furthermore, the use of this device can be extended to other types of vessels, ducts and animal tissues (bones, muscles or organs) as well as vegetal organism or structures (trees, plants , fruits) or any other type of structure in which is necessary to study size, mechanical properties or physiological variations and its response to physical, chemical or environmental stimuli.
At a more basic level, the device can also be useful to measure in a simple, fast and accurate way the section of any structure.
Micro bridle device used for “in vivo” monitoring of arteries
and plants section
Light intensity variations monitored
with the Micro bridle device in response
to section changes in plants flowering stems.
Main applications and advantages
- Adaptable to structures with diverse geometry, composition, hardness, size and nature.
- No influence on its usual behaviour.
- Easy to use.
- Accuracy: from microns to centimetres / 3D image.
- Low cost.
- Real Time.
Ferran Vera Gras
GTQ IMB-CNM (CSIC)
Tel.: +34 – 93 594 77 00