Advanced polymer technologies


Analytical microsystems based on lab-on-chip approaches that integrate chemical sensors have been applied in a great variety of scenarios aiming at detecting target analytes of interest in the biomedical, environmental and food fields. In order to fulfill the requirements for each specific application, different components are included for fluid management, sensor interrogation and/or detection. An important activity of the GTQ group has been directed towards the fabrication of such components making use of non-conventional polymeric materials that provide them with advanced features and a highly added value. In this context, hybrid silicon-based polymeric microstructures have been developed by sol-gel technology to construct filters and light sources that were monolithically integrated into photonic lab-on-chips; carbon nanocomposite materials have been applied in the fabrication of versatile thin-film electrochemical devices; biomimetic polymeric matrices have also been developed as specific receptors to be easily coupled to electrochemical transducers of planar configuration in the fabrication of molecularly imprinted based electrochemical sensors; electrocatalytic nanomaterials have also been generated in the manufacturing of robust electrochemical sensors.

Applications

  1. Absorbance microfilters and solid-state light emitters based on doped hybrid silicon-based polymeric materials fabricated by a soft lithographic approach and easily integrated into all-in-polymer disposable photonic lab-on-chips. 
  2. Silicon oxide light sources based on sub-stoichiometric and silicon nanocrystal structures synthesized by a novel sol-gel polymeric approach, showing photoluminescence behavior modulated in the whole range of the visible spectrum. 
  3. Biomimetic electrochemical sensors based on molecularly imprinted polymeric receptors for the detection of small organic molecules. 
  4. Carbon nanotube polystyrene composites and amorphous carbon composites synthesized by a sol-gel process, both containing inorganic nanoparticles applied to the fabrication of miniaturized electrocatalytic sensors for the monitoring of environmental parameters. 
Optical and fluorescence images of hybrid silicon-based polymeric photonic microstructures
made by micromolding in capillaries soft lithographic technique and applied
to the integration of filters and solid-state light emitters in lab-on-chip devices.
 
Transmission electron microscopy image of a lumininescent sol-gel-based
silicon oxide matrix with embedded silicon nanocrystals applied
to the development of light sources.
Scanning microscopy image of a multiwalled carbon nanotube polystyrene composite
including electrocatalytic CuO and AgO nanoparticles. Material applied to the development
of an electrochemical sensor for the measurement of chemical oxygen demand in wastewater samples.

 

Projects

ITACA: Investigación de tecnologías de tratamiento, reutilización y control para la sostenibilidad futura de la depuración de aguas residuales.
- Program: Contrato INNPRONTA - Ref:
Sat, 2011-10-01 00:00 - Wed, 2014-12-31 00:00
479.059€
143.000€
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BIONANOVIR: Nuevos sistemas bio-híbridos aplicables a vacunas y a biosensores virales: Sensores miniaturizados para la detección de virus basados en estructuras biomiméticas poliméricas de silicio.
- Program: Proyectos Intramurales de Frontera - Ref:
Sat, 2008-11-01 10:00 - Sun, 2010-10-31 10:00
254.000€
82.500€
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SOMIO: Sensores electroquímicos basados en receptores biomiméticos sol-gel para la detección demarcadores protéicos
- Program: PN-Ciencias y Tecnologías Químicas - Ref:
Sun, 2006-10-01 10:00 - Wed, 2009-09-30 10:00
137.940€
65.340€
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SENBIA: Nuevos microsensores basados en nanoestructuras biomiméticas para el diagnóstico de alergias
- Program: Proyectos Intramurales de Frontera - Ref:
Tue, 2005-11-01 10:00 - Wed, 2007-10-31 10:00
100.000€
31.000€
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HIBRIDOS: Sensores químicos miniaturizados basados en materiales híbridos organo-inorgánicos de base de silicio
- Program: Proyectos Intramurales Especiales - Ref:
Wed, 2010-05-26 10:00 - Thu, 2011-08-18 10:00
30.000€
30.000€
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Articles

Cadarso, VJ; Llobera, A; Puyol, M; Schift, H
"Integrated Photonic Nanofences: Combining Subwavelength Waveguides with an Enhanced Evanescent Field for Sensing Applications"
ACS NANO VL.10 (1), 778-785, 2016
12.88
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Gutierrez-Capitan, M; Baldi, A; Gomez, R; Garcia, V; Jimenez-Jorquera, C; Fernandez-Sanchez, C
"Electrochemical Nanocomposite-Derived Sensor for the Analysis of Chemical Oxygen Demand in Urban Wastewaters"
VL.87 (4), 2152-2160, 2015
5.64
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Baez-Gaxiola, MR; Fernandez-Sanchez, C; Mendoza, E
"Gold cluster based electrocatalytic sensors for the detection of formaldehyde"
ANALYTICAL METHODS VL.7 (2), 7-2, 2015
1.82
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Fernandez-Sanchez, C; Rodriguez, JA; Dominguez, C
"Synthesis of sol-gel SiO2-based materials using alkoxydisilane precursors: mechanisms and luminescence studies"
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY VL.73 (2), 417-427, 2015
1.53
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Llobera, A; Juvert, J; Gonzalez-Fernandez, A; Ibarlucea, B; Carregal-Romero, E; Buttgenbach, S; Fernandez-Sanchez, C
"Biofunctionalized all-polymer photonic lab on a chip with integrated solid-state light emitter"
LIGHT-SCIENCE & APPLICATIONS VL.4 (), -, 2015
14.60
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Granado, VLV; Gutierrez-Capitan, M; Fernandez-Sanchez, C; Gomes, MTSR; Rudnitskaya, A; Jimenez-Jorquera, C
"Thin-film electrochemical sensor for diphenylamine detection using molecularly imprinted polymers"
ANALYTICA CHIMICA ACTA VL.809 (), 141-147, 2014
4.39
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Puertas, S; Villa, MD; Mendoza, E; Jimenez-Jorquera, C; de la Fuente, JM; Fernandez-Sanchez, C; Grazu, V
"Improving immunosensor performance through oriented immobilization of antibodies on carbon nanotube composite surfaces"
BIOSENSORS & BIOELECTRONICS VL.43 (), 274-280, 2013
5.44
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Rodriguez, JA; Fernandez-Sanchez, C; Dominguez, C; Hernandez, S; Berencen, Y
"Bulk silica-based luminescent materials by sol-gel processing of non-conventional precursors"
APPLIED PHYSICS LETTERS VL.101 (17), 171908-, 2012
3.84
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Carregal-Romero, E; Fernandez-Sanchez, C; Eguizabal, A; Demming, S; Buttgenbach, S; Llobera, A
"Development and integration of xerogel polymeric absorbance micro-filters into lab-on-chip systems"
OPTICS EXPRESS VL.20 (21), 23700-23729, 2012
3.59
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Gracia Villa, M; Jiménez-Jorquera, C; Haro, I; Gomara, MJ; Sanmartíc, R; Fernández-Sánchez , C; Mendoza, E
"Carbon nanotube composite peptide-based biosensors as putative diagnostic tools for rheumatoid arthritis"
Biosensors & Bioelectronics VL.27 (1), 113-118, 2011
5.36
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Llobera, A; Cadarso, VJ; Carregal-Romero, E; Brugger, J; Dominguez, C; Fernandez-Sanchez, C
"Fluorophore-doped xerogel antiresonant reflecting optical waveguides"
OPTICS EXPRESS VL.19 (6), 5026-5039, 2011
3.75
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Darder, M.; Aranda, P.; Burgos-Asperilla, L.; Llobera, A.; Cadarso, VJ.; Fernandez-Sanchez, C; Ruiz-Hitzky, E.
"Algae-silica systems as functional hybrid materials"
JOURNAL OF MATERIALS CHEMISTRY VL.20 (42), 9362-9369, 2010
4.80
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Fernández-Sánchez, C.; Pellicer, E.; Orozco, J.; Jiménez-Jorquera, C.; Lechuga, L.M.; Mendoza, E.
"Plasma-activated multi-walled carbon nanotube-polystyrene composite substrates for biosensing"
NANOTECHNOLOGY VL.20 (33), 335501-, 2009
3.45
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Mendoza, E.; Orozco, J.; Jiménez-Jorquera, C.; Gonzalez-Guerrero, A.B.; Calle, A.; Lechuga, L.M.; Fernández-Sánchez, C.
"Scalable fabrication of immunosensors based on carbon nanotube polymer composites"
NANOTECHNOLOGY VL.19 (7), -, 2008
3.45
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de la Rica, R.; Baldi, A.; Mendoza, E.; Paulo, A.S.; Llobera, A.; Fernández-Sánchez, C.
"Silane nanopatterns via gas-phase soft lithography"
SMALL VL.4 (8), 1076-1079, 2008
6.53
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Fernández-Sánchez, C.; McNeil, C.J.; Rawson, K.; Nilsson, O.; Leung, H.Y.; Gnanapragasam, V.
"One-step immunostrip test for the simultaneous detection of free and total prostate specific antigen in serum"
Journal of Immunological Methods VL.307 (01/02/11), 1-12, 2005
2.57
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Fernández-Sánchez, C.; McNeil, C.J.; Rawson, K.; Nilsson, O.; Leung, H.Y.; Gnanapragasam, V.
"One-step immunostrip test for the simultaneous detection of free and total prostate specific antigen in serum"
Journal of Immunological Methods VL.307 (1-2), 1-12, 2005
2.57
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Patents

Material compuesto que comprende una matriz porosa de carbón amorfo y nanopartículas de bi obtenible mediante un procedimiento sol-gel, procedimiento de obtención y su uso
Applicant(s): CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
Inventor(s: CESAR FERNANDEZ SANCHEZ [ES]; MARTI GICH GARCIA [ES]; ANNA ROIG SERRA [ES]
Application number: ES201231869 Fri, 2012-11-30 (All day)
Priority number(s): ES201231869 Fri, 2012-11-30 (All day)
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Thesis

Photonic Devices based on hybrid organic-inorganic xerogel polymers
Ester Carregal Romero
Fernández, C; Llobera, A
Universitat Autònoma de Barcelona
Fri, 2012-11-16 (All day)
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MOEMS based on magnetic/photonic sensitive stimuli polymers
Sandra de Pedro
Andreu Llobera Adán, Victor Cadarso Busto
UAB
Fri, 2015-12-11 (All day)
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